miR-193b Down-regulation and miR-196a Up-regulation and Gastric Cancer Clinicopathology and Prognosis

نویسندگان

  • Yong - Ping Mu
  • Song Tang
  • Wen - Jie Sun
  • Wei - Min Gao
  • Mao Wang
  • Xiu - Lan Su
چکیده

Gastric cancer (GC) is the fourth most common malignant tumor worldwide and the second highest in developing countries (Jemal et al., 2010; Parkin, 2001; Siegel et al., 2012). It also ranks as the second leading cause of cancer death worldwide (Camargo et al., 2012; Yin et al., 2012). Moreover, nearly 47% of worldwide gastric cancer cases occur in China alone (Shen et al., 2013b). Currently radical surgery still offers the best chance of long-term survival; however, the five-year survival rate of gastric cancer patients is only about 20-30% (Crew and Neugut, 2006; Yang, 2006). Therefore, it is necessary to develop novel and more sensitive biomarkers to improve

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تاریخ انتشار 2014